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Difference Between Myeloma and Lymphoma

Myeloma vs Lymphoma

Cancer is a formidable disease that occurs not only with a few groups of people but to anybody regardless of age, sex, and race. It is a dreaded illness that fears nothing and no one as it may target either the richest or the poorest. There are also a variety of cancer types which typically are identified through several factors.

Blood cancer is a particular type of cancer that inflicts the blood, bone marrow, and the lymphatic system. Two cancers under this type are myeloma and lymphoma. How do the two differ from each other?

Myeloma is a type of cancer that targets the plasma cells—a component of white blood cells. In human anatomy, almost all new cells are produced by the bone marrow thus making it also the site of growth for abnormally developing plasma cells. On the other hand, lymphoma is a cancer of a part of the immune system. It specifically breeds on lymphocytes–the immune system cells. The lymph nodes, the areas where the lymph is found, become the breeding ground for abnormally dividing lymphocytes.

A various presence of myeloma is termed as multiple myeloma. Meanwhile, lymphomas fall under two types, namely: Hodgkin’s Lymphoma (HL) and Non-Hodgkin’s Lymphoma (NHL). HL has five subtypes while NHL has 30.

Causes of both blood cancers are not confirmed, yet parameters, such as old age, infection, and immunodeficiency, and genetics are considered. There is a higher incidence of myeloma in men than in women.

Symptoms are usually of a wide variety. In myeloma, enlargement and pain of bones are a probable basis while in lymphoma, enlargement and painless swelling of several lymph nodes in the body and the spleen are looked at. Other symptoms may include fever, chills, weight loss, and fatigue.

Diagnosis can be made through blood tests, x-rays, biopsy and urine tests. Staging can also be done to better identify the severity of blood cancers. Bone marrow aspiration is also a standard diagnostic procedure for both cancers.

There is no permanent treatment for myeloma while in lymphoma a combination of therapies are guaranteed to cure the disease. The complexities of cancer are the reason why there is no definitive treatment for each. Medications can also be given by physicians for thorough medical management.


1.Myeloma and lymphoma are two types of blood cancer.

2.Myeloma breeds on plasma cells while lymphoma grows on lymphocytes. Both are essential to the immune system.

3.Classification of myeloma is plainly the same while a number of types and subtypes constitute lymphoma.

4.Primary symptoms for myeloma are enlargement and pain of bones while enlargement and painless swelling of several lymph nodes and the spleen determine lymphoma.

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  1. My husband passed away from Multiple Myeloma, but about 10-12 years prior to that diagnosis he had stage 4 Non-Hodgkins lymphoma, which was treated with chemo. He had no treatment recommended after the lymphoma diagnosis
    The doctor said at that time he had never seen the same patient develop both of those diseases.

  2. Very good article which ended my former confusion.

    I would like to share this article with friends & family.

    Could you send COPY to my personal email (see above)??

    With thanks, Professor Marilyn Hankins Orlando, FL

  3. My wife has both of these cancers now taking chemo so far doing fine

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