5 responses

  1. Ezekiel
    January 24, 2018

    Very detailed


  2. Ashley
    October 27, 2018

    No. This is INCORRECT, DNA Polymerase ALWAYS synthesizes in the 5 to 3′ direction. The lagging strand is synthesized in pieces building from 5 to 3′, once helicase opens up more DNA it goes backwards to sit on the newly exposed DNA then once again moves in the 5′ to 3′ direction.


    • Ginial
      January 8, 2020

      Yes,ashley Grover u r right


  3. F
    October 20, 2019

    RNA primers are necessary for DNA replication in BOTH strands!
    The difference being that the lagging strand needs multiple of them (which leads to the formation of Okazaki fragments) while leading strand synthesis is continuous (only needs one primer).
    The reason it needs multiple is because DNA polimerases can only sinthesize DNA 5’->3’ and adding multiple primers allows for this to happen in the lagging strand.
    However, at the beggining of synthesis in the leading strand A PRIMER IS ADDED so that replication can begin.
    In addition DNA synthesis occurs 5’—>3’ IN BOTH STRANDS.


    • Akshada Jadhav
      May 14, 2020

      I’m really confused,when I read this article,
      You vanished my doubts.☺️


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