8 responses

  1. yawha?!
    February 22, 2010

    Apart from “Epinephrine is a derivative of norepinephrine” this is just wrong, or at least silly. What i assume is supposed to be “Norepinephrine converts glycogen to glucose while [epinepherine] increases the catabolism of glycogen” isn’t a difference. converting glycogen to glucose is the same as catabolism of gylcogen. Is it not?

    • Adeyemi Blessing
      February 7, 2012

      Norepinephrine and epinephrine differ in their effects on blood vessels.Norepinephrine causes vasoconstriction of all blood vessels whereas epinephrine causes vasoconstriction of blood vessels supplying the skin and gut and vasolidation of blood vessels to muscles and the brain.

  2. Ian
    August 27, 2010

    So much of this article is incorrect! Norepinephrine definitely does NOT calm the system down. These are both neurohormones of the sympathetic nervous system–aka the “fight or flight” system. Epinephrine, not NE, increases blood glucose by breaking down glycogen. This is a very poor article.

  3. Giantcrab
    September 17, 2010

    I never read anything about norepinephrine being a hormone/neurotransmitter that calms the system down.

  4. Dom
    January 24, 2011

    Epinephrine (/adrenaline) supplied by the Renal medulla does however relax Beta 2 adrenergic receptors in the airway causing bronchodilation – increasing the size of the airway lumen and making it easier to breath. Another example of a Beta 2 agonist which performs a very similar task is Salbutamol, which you will find in a blue inhaler (usually a 100mg dose). I imagine this greatly calms down the sufferer of an asthma attack.

  5. harry
    March 17, 2011

    Reply to Ian’s answer:
    NE also breaks down glucose from glycogen when in need.
    Ref: http://en.wikipedia.org/wiki/Norepinephrine

  6. Khairuzzaman Gazi
    September 23, 2011

    epi and nor-epi (aka, adrenaline and noradrenaline respectively) both are catecholamines. they both have similar chemical structure and function with few differences…they are both sympathomimetic (responsible for fight or flight response) which is somewhat opposite to parasympathetic action..nor epinephrine is released from all sympathetic effector organ nerve terminals and acts mostly at the vicinity so its a neurotransmitter….epinephrine is secreted by adrenal medulla( which is homologous to sympathetic neuron cells) and is circulated via blood and acts on target tissue/organ away from where it is released; so it is a hormone…..nor-epinephrine works on alpha 1, alpha 2, and beta 1 receptors……but epinephrine works on all alpha 1, alpha 2, beta 1 and beta 2 receptors…….by working on beta 2 receptors which are found on lungs’ airway smooth muscle and in skeletal muscle’s blood vessels, epinephrine dilates those air tubes and skeletal muscle’s blood vessels which is crucial in fight or flight response or during exercise….

  7. Norman
    February 20, 2015

    Epi and Norepi are both stimulants therefore neither calms anything down . Just use local anes in surg Xylocaine with epi and see what happens to the heart rate .

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