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Difference Between Dextroamphetamine and Adderall

Dextroamphetamine vs Adderall

Dextroamphetamine and Adderall are both drugs which trigger the central nervous system, particularly the brain. They have a profound effect on the nervous system.

Dextroamphetamine is a drug. It is classified as a psychostimulant. It is mainly used to prevent drowsiness and decreased focus. Adderall, on the other hand, is also a stimulant drug. It contains amphetamine and other substances.

Dextroamphetamine was first discovered in Berlin, Germany during 1887 by Lazar Edeleanu. It was used during the 1930′s to treat depression, attention disorders, and obesity. Not until the 1970′s was a law passed in the US Congress to make this drug a prohibited drug that would not be dispensed without a doctor’s prescription. This is due to people abusing its stimulant effects. On the other hand, Adderall was first introduced on the market during 2001 by Shire Pharmaceuticals.

Since Dextroamphetamine is a stimulant, it keeps the client awake and alert most of the time. It also suppresses hunger. This drug was approved for medicating children who are diagnosed with ADHD or Attention Deficit Hyperactive Disorder. It was also approved for narcolepsy or extreme sleepiness. On the other hand, Adderall is mainly used to treat ADHD and narcolepsy by blocking certain brain receptors. It is said to be the best drug of choice for treatment of ADHD compared to Dextroamphetamine.

Dextroamphetamine, however, has a lot of unwanted side effects, such as, headache, anorexia, restlessness, tachycardia, palpitations, and tremors. For psychological effects, it is said to make the person happy and stress free. But Adderall has addtional harmful adverse effects, such as, a sudden rise of blood pressure which may lead to stroke and death. It should not be given to people with cardiac-related problems. It also increases the risk of seizures for patients who already have seizures. It is also reported to suppress the appetite.

Adderall is contraindicated to many other drugs compared to Dextroamphetamine. It is contraindicated to drugs, such as, SSRI’s and MAOI’s.

To sum it all up, there are no major differences between the two drugs. However, they differ in side effects and adverse effects which can kill people who are medicating with them.



Dextroamphetamine and Adderall are both psychostimulants, but they differ in the mechanism of action.

Dextroamphetamine is not usually contraindicated to take with other drugs unlike Adderall.

Dextroamphetamine has a lot of side effects and withdrawal effects to humans compared to Adderall.

Adderall has a major adverse effect which can kill a human in an instant compared to Dextroamphetamine.

Adderall is a better drug for treatment of ADHD compared to Dextroamphetamine.

Adderall is contraindicated with many other drugs. It cannot be taken simultaneously compared to Dextroamphetamine.

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  1. just about everything on this page is wrong. Aderral contains about 75% Dextroamphetamine. Just about anything that applies to one applies to the other

    • There are most certainly misrepresentations in this article, but some truths as well. This is a classic, “don’t believe everything you read on the internet” case. *Talk to your Dr.*

      I would also advise the writer to abstain from using the word contraindicated until it’s proper context and meaning are understood. ***Especially in cases where you are presenting a double negative or a nonsensical statement (ie: #2 of the summary)*** It creates quite the opposite effect of “appearing learned”.

      There are two types of contraindication;
      Relative contraindication: Which means that caution must be exercised when two drugs are used together. (BUT, if the benefits outweigh the risk it can be deemed o.k.)
      Absolute contraindication: In this case, a substance could ultimately have life-threatening side effects and medications that fall into this category should be avoided.
      Your article is also disjointed and jumps back and forth…. ALL GOOD REASONS NOT TO BELIEVE EVERYTHING THAT YOU READ ON THE INTERNET…

    • Since switching from dextrostat to Adderall~my blood pressure has spiked over 20 points both directions! Explain this!

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