41 responses

  1. DR ARSHAD AHSAN
    July 11, 2010

    good information thanks

    Reply

  2. Kim
    August 10, 2010

    Thank you so much for offering a comprehendable explanation for this!

    Reply

  3. Nick
    March 24, 2011

    Thanks for the above – clear and concise.

    I have seen test results for long term chronic bacterial infection, i.e. several years after initial infection, that have a significant igM and a negative igG. What is occuring in this instance?

    Reply

    • jeff siegel
      July 5, 2017

      I would like to understand this also as one of my parents tick infection results came back with this issue and its puzzling .Is it possible they have an immune deficiency and are not making igg antibodies to this bacteria? I myself have primary immune defficiency .low IG1 and IGa. chronic lyme and coinfections as well.

      Reply

      • ELIZABETH ALBAN
        May 29, 2018

        Borrelia bacteria are able to change their outer surface proteins during infection and because of this they represent a constantly new antigen stimulation. This means that the body may respond with IgM throughout infection. This effect is noted in the data sheets of some Lyme tests, but is not recognised by many doctors.

        Reply

  4. Kamaljit Bahra
    September 6, 2011

    Thank you very much for offering very clear and concise description between IgG and Igm. It made it easier to interpret one of our resident’s test results.

    Reply

  5. Debbie
    January 7, 2012

    Thank you so much! I have low numbers in both of these and have difficulty in explaining what they are to people. I have trouble understanding it as it is so new to me! I printed out the article to keep with me.

    Reply

  6. dr.Bilawal khan
    October 23, 2012

    thanks for iformation…

    Reply

  7. pearl
    October 21, 2013

    thank you so much for this clear and easy explanation between igG and igM now i have a better understand,

    Reply

  8. Jatin
    February 1, 2014

    Very well explained. thanks !

    Reply

  9. Sami
    June 5, 2014

    Thank u sir for info

    Reply

  10. Shirley
    August 21, 2014

    Thank you very much! Very clear and useful.

    Reply

  11. Hasitha Madushan
    September 8, 2014

    Thanks for this intresting explanation about IgM and IgG

    Reply

  12. Miosi Malonzo
    March 7, 2015

    Thank you for clear explanation because I got afraid I don’t have Igm in my body when I got sick it’s only Igg.. Now it’s clear to me that after a week it will comeback.

    Reply

  13. nasir
    March 14, 2015

    sir pls tell that my test typhoid igm positive and igg negative.thanks

    Reply

  14. Sarah
    October 7, 2015

    Had some tests done and my varicella IgG was over 3,000 and the Igm was 1.12 positive. I am not having any shingles…what does this mean.

    Reply

    • Siddu
      August 20, 2017

      Nice and brief information

      Reply

  15. Amit
    October 9, 2015

    Thanks for giving wonderful knowledge about the captioned subject…

    Reply

  16. Tal
    October 19, 2015

    thanks very good and short explanation!

    Reply

  17. Carvo
    June 29, 2016

    This is a wonderfull piece of information,I need to print this.thanks

    Reply

  18. Roopam
    November 25, 2016

    Hello my name is Roopam and I just want to know that my IGg test is 107.10 and is there any risk in pregnancy

    Reply

  19. aditya
    December 5, 2016

    I got tested for chlamydia igg and igm..
    igg is 1.33 positive
    igm is 0.38 negative
    wat shud I do now…I dont know wat to do

    Reply

  20. precious Awulo
    December 13, 2016

    I really find this concise and clear information helpful. Tnx a lot

    Reply

  21. Shahab Farooqi
    January 25, 2017

    Thank you sir for presenting such an easy learning approach to the difference of IgM and IgG.
    I have a question. Why in some people IgM is always positive for typhoid? Why don’t they get cured??

    Reply

  22. Interesting
    May 19, 2017

    Once the IgG antibody is created and lets say the disease comes back, will you still see a positive IgM again?

    Reply

  23. kelvin
    June 8, 2017

    thanks for your info is useful

    Reply

  24. abid nawaz
    July 30, 2017

    Thanks so much
    Its cleared my idea about IgM and IgG antibodies.

    Reply

  25. Alisha
    August 9, 2017

    Thank for giving information …..its very useful

    Reply

  26. aslam khan
    August 30, 2017

    Tnks inform igm

    Very very tnks

    Reply

  27. v.s.chauhan
    September 8, 2017

    Appreciate for good explanation.

    Reply

  28. Mohammad Shabbir Sulehria
    October 8, 2017

    Thanks. It is v. Useful information for me.

    Reply

  29. Mohammad Shabbir Sulehria
    October 8, 2017

    Thank you. Informative details.Good job.

    Reply

  30. Forgive Gamloanyi
    October 10, 2017

    Thank you so much doctor for this explanation. My brother tested Typhoid IgG and IgM positive. He feels week and also have high fever. He behaves abnormal for a short time. Doctor what is the natural remedy and please let me know what can be done to get my brother back to normalcy

    Reply

    • Dd2
      December 25, 2017

      I wish you a Merry Christmas (the day that I’m writing this comment) and a Happy New Year!

      To the future commenters: This is a “Difference Between” Site…NOT a doctor’s office…I have my own blood issues that caused me to seek out this article but I would NEVER seek medical advice online from a total stranger ESPECIALLY on a website that had NOTHING to do with medical issues and MOST ESPECIALLY with my blood work!!! Please stop asking for medical advice! If you read the above comments, you will see that it’s been done…over and over and over again…and NOT ONCE HAS THE AUTHOR REPLIED!!! Thank them for the article or give whatever other comment but stop asking for medical advice! I’m sorry if I come across as rude but there were way too many people that decided to use this article to try to get free medical advice and some didn’t even bother to thank the author for the well written article that they were commenting on! That upset me because the author, whatever they were doing in their life then, took the time to share their well researched, clearly written, and, best of all, mostly easy to understand article with the rest of us! I truly appreciate the effort they must have put into researching and writing it and find the place to put it for the rest of us to find!

      To the author of this article…thank you for this, clearly, well written article explaining the difference! As you can see from the number of people seeking medical advice on here, you come across as quite knowledgeable, concise, and professional…as well as approachable, I guess. The way I read it was, even if you DID work in the medical field back when you published this article though, you did NOT do so in a professional capacity or you WOULD have used your title. Even if you HAD used “Dr.” or “M.D.” or whatever was applicable, you didn’t end your article by asking for people to seek you out for medical advice! Those that did so without you specifically advertising it and with you, clearly, not answering anybody else when they tried asking…because what sane person would open themselves up to lawsuits by giving medical advice to strangers online unless it’s through their employer’s (such as the “Message your Doctor” feature that many physicians offices have now while some even have it where you can video chat with them)?!? Anyway, I wanted to say again…Thank you Purpa Mukherjee! I still have MANY questions…because your article doesn’t give examples of possible autoimmune disorders for IgM and IgG high and low levels. Of course, I’m sure that wouldn’t quite fit into this website’s “Difference Between” niche and would be extraneous data as well as too numerous to list probably…I’m just trying to learn more about my own blood work so it would have been nice to know what the possibilities were. Especially since, based on your article, I may be an oddball but I’ll leave that up to my doctors to figure out.

      Reply

  31. Melissa Recker
    November 24, 2017

    Ok so im little confused. I was tested for herpes and my test came back as

    Igg- .46. Negative
    Lgm- 1.80 equvocal

    Does that mean that i am positive

    Reply

  32. vipul
    February 11, 2018

    Thanks to giving this information it’s very useful. …

    Reply

  33. Livin Sabio
    March 17, 2018

    This is the best explanation I’ve ever encounter in order to understand the function/difference between both of these amazing antibodies. Thank you very much. I used to always get confused but after reading this thoroughly explained comparison I am certain about the function of each.

    Reply

  34. Mohammad
    June 15, 2018

    The best explanation ever seen
    Thanks

    Reply

  35. Ankit
    August 13, 2018

    I am nonmedico. But excellent information and valuable too..

    Reply

  36. ralph a. applegate
    September 9, 2018

    Only answer if you have a basis for your answer !Will 7 days consecutive exposure to breathing Roundup(Polyethoxylated Tallow Amine in it ),after days delay , to illness , and effect of Diagnosis IgM of 8980 mg./dL would be proof of cause of Non Hodgkins Lymphoma ?

    Reply

  37. ralph a. applegate
    September 9, 2018

    An opinion without a basis is not acceptable , whatsoever ! That is not science ! Except somehow , for lawyers , someone is excusing them .

    Reply

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